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The post Important work from our team in Science Magazine today, showing how our diagnostic orchestrator can reason through complex medical cases, achieving greater diagnostic accuracy while reducing testing costs. appeared first on Source.
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NEW YORK, Oct. 22, 2026 -- WHY: Rosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of Build-A-Bear Workshop, Inc. (NYSE: BBW) resulting from allegations that Build-A-Bear may have issued materially misleading business information to the investing public.
Etiquette refers to the manners and behaviours that show respect, consideration, and professionalism, helping people communicate effectively, build trust, and maintain positive relationships. The book covers social, professional, and digital etiquette, emotional intelligence, and civic responsibility. Authored by Dr. Philip Skyes and formatted by Wadsworth -- The Art of Etiquette: Building Respectful Relationships an
Joseph Lassen outlines the federal and Texas rules military families should understand before filing, from the 50 percent cap and the 10/10 rule to Howell v. Howell and the Survivor Benefit Plan and TRICARE deadlines. -- As Veterans Day approaches on November 11, The Law Firm of Joseph Lassen, a San Antonio military divorce attorney and family law firm, is explaining how military retirement pay, VA disability compens
Hong Kong, Oct 23, 2026 - HighTide Therapeutics, Inc. (02511.HK), an innovative biopharmaceutical company specializing in the development of multifunctional, multi-targeted therapies for cardiovascular–kidney–metabolic (CKM) diseases, today presented new preclinical findings for HTD1801 in autosomal dominant polycystic kidney disease (ADPKD) at Kidney Week 2026, the 59th Annual Meeting of the American Society of Nephrology (ASN), in Denver, US. The findings demonstrate potent inhibitory activity of HTD1801 against cyst expansion in ADPKD. ADPKD is the most common inherited kidney disorder, characterized by progressive cyst formation and kidney failure by age 60 in approximately 50% of patients. Although existing treatments are available to slow disease progression in certain patients, safety risks and eligibility limitations leave substantial unmet medical needs in ADPKD. HTD1801 targets the AMPK–NLRP3 axis by activating AMPK, suppressing cAMP-driven epithelial cyst proliferation while inhibiting NLRP3 to mitigate renal inflammation and fibrotic remodeling, thereby potentially targeting key pathological processes in ADPKD. In this study, the effect of HTD1801 on forskolin (FSK)-induced cyst expansion was evaluated in PKD1−/− human iPSC-derived nephron organoids, with metformin and tolvaptan as reference comparators. The results showed that HTD1801 significantly reduced the median cystic area fraction to 10.70%, compared with 20.40% in the FSK model control group. Meanwhile, organoids with a low cystic burden (<20%) increased from 46.9% in the model control group to 97.3%, while organoids with a high cystic burden (≥30%) decreased from 8.2% to 0%. By comparison, metformin reduced the median cystic area fraction to 13.12%, while tolvaptan did not alter cyst burden, as this model does not respond to tolvaptan. These findings further expand the potential multidimensional renal benefits of HTD1801. Previous studies have demonstrated the potential of HTD1801 to improve metabolic abnormality-associated renal impairment. HTD1801 effectively suppresses cyst expansion in PKD1-mutant human nephron organoids, validating its dual effects of AMPK activation and NLRP3 inhibition in ADPKD pathogenesis. These preclinical findings provide a strong rationale for further clinical investigation of HTD1801 to explore its potential as a disease-modifying therapy for ADPKD. They further highlight the therapeutic potential of HTD1801 for patients with ADPKD and other chronic kidney diseases (CKD), particularly those currently underserved by existing treatment options. Presentation Title: HTD1801 Suppresses Cyst Expansion in PKD1-Mutant Nephron Organoids: Evidence for AMPK-NLRP3 Axis Efficacy in ADPKD Presentation Number: TH-PO0204 Date and Time: October 22, 2026, 10:00 AM–12:00 PM MDT Format: Poster Presentation Session: ADPKD and Cystic Kidney Disease – 1 [PO1201-1] Presenter: Dr. Filip Surmont, Chief Medical Officer of HighTide Therapeutics “ADPKD continues to pose a substantial unmet medical need, as progressive cyst growth can lead to deterioration of kidney function and ultimately kidney failure, underscoring the need for effective therapies that can inhibit cyst growth,” said Dr. Filip Surmont, Chief Medical Officer of HighTide Therapeutics. “The significant suppression of cyst expansion observed with HTD1801 in this study provides new scientific evidence to support its further development in ADPKD and highlights its potential as a disease-modifying therapy. We will continue to advance research on HTD1801 to further validate these findings and explore its potential therapeutic value in kidney diseases.”
ORLANDO, FL, Oct 23, 2026 - MicroVision, Inc. (NASDAQ: MVIS), a leader in advanced perception solutions for industrial, security and defense, intelligent infrastructure, and automotive applications, today announced the much-anticipated commercial production launch of MOVIA™ Pro, shipping sensors to meet customer demand. MOVIA Pro is the company’s next-generation short-range lidar sensor uniquely engineered to deliver differentiated sensing performance and onboard perception capabilities, with flexible integration across intelligent infrastructure, unmanned aerial, industrial robotics, and other emerging autonomous applications. As the lidar industry transitions toward solid-state architectures that enable cost-effective sensing solutions, MicroVision’s MOVIA Pro is designed to deliver enhanced short-range detection performance for demanding applications. By combining advanced sensing capabilities with onboard perception, MOVIA Pro makes high-performance lidar more accessible across a broader range of autonomous and intelligent systems. MOVIA Pro joins the company's broader portfolio of short- and long-range lidar technologies, airborne sensing solutions and advanced perception software, providing customers with configurable solutions for a growing range of operating environments. The launch of MOVIA Pro reinforces MicroVision's transformation into a diversified perception technology company focused on delivering commercially ready solutions for industrial, intelligent infrastructure, security and defense, and emerging autonomous applications. "We’re thrilled to meet pent-up customer demand with this production launch of MOVIA Pro,” said Glen DeVos, CEO of MicroVision. “Customers are ready to progress from evaluation of prototypes to launching commercial programs, and we are pleased to support their progression. Our Orlando-based state-of-the-art production facility is manufacturing MOVIA Pro to meet the increasing demand. DeVos continued, "With MOVIA Pro, we've combined high-performance sensing with onboard computing, an open software framework and industrial-ready connectivity. This is one device that can sense, perceive, and act, providing customers with a more integrated and adaptable solution." One Sensor That Sees, Understands, and Enables Solutions at the Edge MOVIA Pro is MicroVision’s production-ready version of MOVIA S, loaded with high-performance features and a differentiation that extends beyond sensing hardware. Built around an integrated processing architecture, MOVIA Pro enables perception software to run directly on the sensor through MicroVision's Open Software Framework. This allows developers and customers to build, deploy, and update applications on the device, rather than relying exclusively on external computing hardware to interpret point-cloud data. The architecture enables MOVIA Pro to generate sensing information, process that information into actionable perception outputs, and communicate results directly to connected systems. Key capabilities include: Onboard perception, edge AI, and open software: Processes point-cloud data directly on the sensor to generate object-level information, supporting AI at the edge and reducing reliance on external computing devices. Multi-echo sensing enhances perception by capturing multiple returns from a single emitted pulse, helping detect objects in challenging conditions. An open, Linux-based software framework enables customers to develop, deploy, and update perception applications. Flexible connectivity and industrial integration: Supports CAN, Gigabit and 100Mbit Ethernet, and industrial-ready I/O and connectors to simplify integration with industrial equipment, vehicles, and control systems. Software-defined evolution: Enables capabilities and enhancements through software updates, with a foundation for future-edge computing and AI-ready capabilities. By combining sensing and perception in a single device, MOVIA Pro is designed to reduce system complexity, cabling and external hardware requirements while supporting more efficient integration, maintenance and future upgrades. Movia Pro is MicroVision’s next-generation short-range lidar sensor that delivers integrated perception and multi-echo sensing, built for flexible integration across various commercial applications. Purpose-Built for High-Value Commercial Applications MOVIA Pro is designed to support a broad range of commercial and defense applications, with MicroVision prioritizing markets where advanced short-range perception can address immediate operational challenges and enable new levels of automation. Its configurable sensing and perception architecture supports applications across: Aerial Systems – Civil and Defense: Supporting navigation, obstacle awareness, mapping, environmental perception and autonomous operations for unmanned platforms, where compact sensing, onboard processing and reliable perception are critical. Intelligent Transportation and Smart Infrastructure: Enabling intelligent intersections, traffic monitoring, automated traffic enforcement, infrastructure surveillance and connected transportation systems through high-resolution sensing, broad field of view, and industrial connectivity. Anonymized sensing capabilities can support monitoring applications where privacy is a consideration. Warehouse and Industrial Automation: Supporting obstacle detection, environmental awareness and automated navigation for autonomous mobile robots (AMRs), automated guided vehicles (AGVs), forklift advanced driver-assistance systems and other intelligent industrial equipment. Continuous near-field coverage, multi-echo capabilities and onboard perception help address dynamic environments where people, equipment and autonomous machines operate in close proximity. Security, Defense, and Emerging Applications: Supporting infrastructure protection, autonomous ground systems, off-road unmanned ground vehicles, marine systems, commercial vehicles and selected automotive applications, including low-speed autonomy, blind-spot detection and off-road assistance. Availability and Product Information MOVIA Pro is now available for customer orders. For additional product information, visit https://microvision.com/sensors/movia-pro. For inquiries, please contact us here. About MicroVision MicroVision is defining the next generation of lidar-based perception solutions for industrial, security & defense, infrastructure, and automotive markets. As the industry moves beyond proof of concept toward value, deployment, and commercialization, MicroVision delivers integrated hardware and software solutions designed for real-world performance, automotive-grade reliability, and economic scalability. With engineering centers in the U.S. and Germany, MicroVision leads the industry in depth and breadth of its portfolio, with both short- and long-range lidar solutions, featuring solid-state sensors, advanced sensor architectures, design-to-cost engineering, and open software solutions. For more information, visit the company's website at www.microvision.com, on Facebook at www.facebook.com/microvisioninc, and LinkedIn at www.linkedin.com/company/microvision/. MicroVision, MicroVision HALO, IRIS, MOVIA, MOSAIK, and SENTINEL are trademarks of MicroVision, Inc., and SCANTINEL is a trademark of Scantinel GmbH, in the United States and other countries. All other trademarks are the property of their respective owners. Investor Relations Contact: Jeff Christensen Darrow Associates Investor Relations MVIS@darrowir.com Media Contact: Heidi Davidson - For MicroVision heidi@galvanizeworldwide.com (914) 441-6862
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