1,100 press releases in English indexed under food & drink.
At wine2wine Vinitaly Business Forum New York, America's Master Sommeliers and four leading Italian producers confront the questions nobody asks out loud: why a great wine doesn't get listed, who sets the price, and what it takes to stay on the list.. NEW YORK, Oct. 24, 2026...
CAMBRIDGE, Mass., Oct. 24, 2026 -- Parabilis Medicines (Nasdaq: PBLS), a clinical-stage biopharmaceutical company dedicated to creating extraordinary medicines for patients with serious diseases by unlocking historically undruggable targets, today announced updated safety and efficacy data for zolucatetide, the first and only direct inhibitor of the β-catenin:TCF interaction, in patients with desmoid tumors. The data were presented today in an oral presentation at the European Society for Medical Oncology (ESMO) Congress 2026, taking place October 23–27, 2026, in Madrid, Spain. The updated results, based on a June 22, 2026, data cutoff, include data from both the dose escalation and dose optimization portions of the ongoing Phase 1/2 trial and reinforce the strong efficacy and favorable safety and tolerability profile observed with zolucatetide. Among response-evaluable patients who began treatment at a starting dose of ≥450 mg, zolucatetide demonstrated an objective response rate (ORR) of 72.2% (13/18) in a 32-week landmark analysis. A disease control rate (DCR) of 100% was observed across all 46 response-evaluable patients who received a starting dose of ≥450 mg, with no disease progression. Data from a three-arm randomized dose optimization trial supported selection of a 450 mg weekly induction regimen administered for four cycles, followed by 300 mg every two weeks for long-term maintenance. Following productive end-of-Phase 2 discussions, Parabilis has reached alignment with the U.S. Food and Drug Administration (FDA) on the selected dose and regimen, on the use of a placebo-controlled study design, and on progression-free survival (PFS) as the primary endpoint for registrational development. Parabilis plans to initiate the randomized, double-blind PEDESTAL Phase 3 trial (Phase 3 Evaluation of DESmoid Tumor Activity with zoLucatetide) in the first half of 2027, with topline results anticipated in 2029. “Desmoid tumors are chronic and life-altering for patients, often affecting people at a young age, and patients need treatments that can deliver rapid, deep and durable tumor responses with a tolerability profile suited for long-term treatment,” said Mathai Mammen, M.D., Ph.D., Chairman, CEO and President of Parabilis Medicines. “We designed zolucatetide to directly inhibit β-catenin:TCF, a historically undruggable target at the heart of the biology driving these tumors. The depth and consistency of responses we are seeing, together with the favorable safety and tolerability profile observed to date, reinforce our conviction that zolucatetide has the potential to deliver a truly differentiated medicine and meaningfully expand the number of patients who can benefit from treatment. We are very pleased with the clarity of the FDA’s feedback on our registrational development strategy, and with our Phase 3 regimen selected, we are moving with urgency to bring this medicine to patients.” Updated Phase 1/2 Results As of the June 22, 2026, data cutoff, 76 patients with desmoid tumors had been enrolled and treated across all dose levels in the dose escalation and dose optimization portions of the trial. Median age was 37 years (range 19–80), and 69.7% of patients were female. The population included both patients who had previously been treated with and failed gamma-secretase inhibitors (GSIs) and patients naive to GSIs.
OCHA says that more aid continues to arrive in northern Ethiopia. Food assistance is reaching tens of thousands of people affected by conflict and El Niño-related impacts across the northern regions. However, humanitarian needs continue to outpace the ongoing response, making additional resources and sustained access essential. In the Tigray region, humanitarian partners report several incidents of drone strikes impacting civilians and essential infrastructure. This includes a strike that hit a local NGO’s humanitarian warehouse on Wednesday. The extent of the damage and the loss of humanitarian supplies are still being assessed. Multiple drone strikes were also reported between 15 and 21 October in the eastern Amhara region, according to partners. Reports indicate that the strikes killed at least 15 civilians and injured several others, including children. Schools were also damaged. The UN reiterates its call to protect civilians and civilian infrastructure. Distributed by APO Group on behalf of Office for Coordination of Humanitarian Affairs (OCHA).
-- On October 16–18, the 2026 Chishui River Forum, jointly initiated by the Brand Work Office of Xinhua News Agency, China Economic Information Service, and China Moutai, was held in Maotai Town, Guizhou Province. The Forum brought together representatives of international liquor companies and organizations to draw on Eastern wisdom in terroir-based brewing and explore new pathways for industrial development that pro
-- The World Famous Liquor Brands Sustainability Index Report (2026) (hereinafter referred to as the “Report”), compiled by the Xinhua Index Research Institute, was officially released at the 2026 Chishui River Forum on October 17. The Report finds that the 30 representative liquor and wine brands worldwide demonstrate a development profile characterized by “solid foundations in quality and brand visibility, alongsid
Can Regional Advantages Become an Excuse for Complacency? How Are Chinese and International Producers Responding to Evolving Consumer Preferences? -- At the 2026 Chishui River Forum on Oct. 17, jointly initiated by the Brand Work Office of Xinhua News Agency, China Economic Information Service (CEIS) and China Moutai, representatives of the global wine and spirits industry, alongside experts and scholars from China,
New honours in Louisiana and Georgia lead a broader dining selection spanning 44 cuisines, with Chattanooga venues among the region’s recognised establishments. KEY TAKEAWAYS Dakar NOLA in New Orleans, So. Fox in Atlanta and Uberto Restaurant in Gay, Georgia, each received One MICHELIN Star in the 2026 selection. The guide lists 265 restaurants across 44... Read the full news article
Scottsdale, AZ, Oct. 23, 2026 — Black Rock Coffee Bar, the Oregon-born boutique coffee chain celebrated for its specialty coffees, teas, smoothies, and signature Fuel® energy drinks, is growing its footprint in California with the opening of a new store in Rancho Cucamonga. The store, located at 11370 Fourth St, will officially open … Continue reading "Black Rock Coffee Bar Continues Expansion in California with New Rancho Cucamonga Location"
Statewide initiative mobilized local lodges across Utah to support emergency shelters, food security, domestic violence centers, and care for vulnerable populations SALT LAKE CITY, Oct. 23, 2026 -- On Saturday, October 17, 2026, 200+ members of the Grand Lodge of Free &...
TORONTO, October 24, 2026--Slate Grocery REIT (TSX: SGR.U) (TSX: SGR.UN) (the "REIT"), an owner and operator of U.S. grocery-anchored real estate, announced today that it has obtained an interim order (the "Interim Order") of the Ontario Superior Court of Justice (Commercial List) (the "Court") in conn